Biomarkers-Validation and Verification

The discovery of biomarkers requires highly confident identification of candidates for biomarkers with simultaneous quantitation information to indicate which proteins are changing in response to disease to a statistically relevant level. Because of natural medical or biological variability, a large number of samples need confirmation of candidate biomarkers identified in the discovery phase. The challenge is to develop a fast, targeted analysis method capable of analysing as many identified candidates as possible in minimally hundreds and potentially even thousands of samples.

 

  • Identify new medical biomarkers
  • Prioritize new protein targets for diagnostic testing of disease progression
  • Reaction to drug therapy

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