Biomarkers for Bipolar Disorders

Biomarkers research in bipolar disorder is a new field with an expanding knowledge. It is associated with imbalances in various biological systems, including the immune system, neurotrophins, neuroendocrine axis, and oxidative stress. External molecules related to the pathophysiological mechanisms underlying the bipolar disorder may be a potential biomarker of the disease. Bipolar disorder is correlated with structural and functional changes in neuroimaging consistent with brain atrophy, including expansion of lateral ventricles and loss of prefrontal cortex and amygdala volumes. Bipolar disorder peripheral and neuroimaging findings may reflect neuroprogressive disease processes. It seems unlikely that a single candidate biomarker will tap the clinical and biological heterogeneity of bipolar disorder.

  • Bipolar effective
  • Brain mapping
  • Heterogeneity of bipolar disorder

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